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Glycan profiles of gp120 protein vaccines from four major HIV-1 subtypes produced from different host cell lines under non-GMP or GMP conditions.

Products Related Product# 1039 HIV-1 YU2 (M Tropic)Envelope Glycoprotein gp41 Product# 1081 HIV-1 gp120 (ADA) Product# 1011 HIV-1 gp120 (subtype C) Product# 1031 HIV-1 gp120 (YU2) Abstract Envelope glycoprotein (Env) of human immunodeficiency virus type 1 (HIV-1) is an important target for the development of an HIV vaccine. Extensive glycosylation of Env is an important.

Posted on March 12, 2020

ImmunoDX

DNA Vaccine Molecular Adjuvants SP-D-BAFF and SP-D-APRIL Enhance Anti-gp120 Immune Response and Increase HIV-1 Neutralizing Antibody Titers

Products Related top24,gp41,gp120,gp160 Product#1103 HIV-1 p24 Monoclonal Antibody Product#1091 Recombinant HIV-1 MN gp41 Envelope Protein (E.coli) Product#1001 Recombinant HIV-1 IIIB Envelope Glycoprotein gp120 (Baculovirus) Product#1024 Recombinant HIV-1 MN Envelope Glycoprotein gp160 (Baculovirus) INTRODUCTION It is generally believed that broadly.

Posted on March 02, 2020

ImmunoDX

Influence of the Envelope gp120 Phe 43 Cavity on HIV-1 Sensitivity to Antibody-Dependent Cell-Mediated Cytotoxicity Responses.

Products Related Product#101 gp120 Capture Elisa Kit Product# 1081 HIV-1 gp120 (ADA) Product# 1011 HIV-1 gp120 (subtype C) INTRODUCTION Entry is the first step of the human immunodeficiency virus type 1 (HIV-1) replication cycle and requires the mature viral envelope glycoproteins (Env), which results from the proteolytic cleavage of the gp160 precursor Env into the.

Posted on February 28, 2020

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HIV/AIDS Vaccine Candidates Based on Replication-Competent Recombinant Poxvirus NYVAC-C-KC Expressing Trimeric gp140

HIV/AIDS Vaccine Candidates Based on Replication-Competent Recombinant Poxvirus NYVAC-C-KC Expressing Trimeric gp140 and Gag-Derived Virus-Like Particles or Lacking the Viral Molecule B19 That Inhibits Type I Interferon Activate Relevant HIV-1-Specific B and T Cell Immune Functions in Nonhuman Primates

Posted on February 25, 2020

ImmunoDX

Rationally Designed Immunogens Targeting HIV-1 gp120 V1V2 Induce Distinct Conformation-Specific Antibody Responses in Rabbits.

Products Related Product#101 gp120 Capture Elisa Kit Product# 1081 HIV-1 gp120 (ADA) Product# 1011 HIV-1 gp120 (subtype C) INTRODUCTION The HIV-1 envelope (Env) complex of glycoproteins gp120 and gp41 is the target for neutralizing antibodies (nAbs) induced in HIV-1-infected patients and for HIV/AIDS vaccine development (1,2). Glycoprotein gp120 has been.

Posted on February 24, 2020

ImmunoDX

Stabilization of a soluble, native-like trimeric form of an efficiently cleaved Indian HIV-1 clade C envelope glycoprotein

Introduction HIV-1 Env3is a trimer of heterodimers of gp120 and gp41 that are associated non-covalently after cleavage of gp160 by an endogenous protease (1). The trimeric Env on the HIV-1 surface facilitates viral entry into the host cell through receptors and is the target of neutralizing antibodies (2). In some rare subjects, broadly neutralizing antibodies (bNAbs) are spontaneously.

Posted on February 21, 2020

ImmunoDX

Adaptation of HIV-1 to cells with low expression of the CCR5 co-receptor.

Products Related Product# 1039 HIV-1 YU2 (M Tropic)Envelope Glycoprotein gp41 Product# 1081 HIV-1 gp120 (ADA) Product# 1011 HIV-1 gp120 (subtype C) Product# 1031 HIV-1 gp120 (YU2) Introduction The metastable human immunodeficiency virus (HIV-1) envelope glycoprotein (Env) trimer ((gp120/gp41)3) mediates entry into target cells (Wyatt and Sodroski, 1998)..

Posted on February 19, 2020

ImmunoDX

HIV-1 Env and Nef Cooperatively Contribute to Plasmacytoid Dendritic Cell Activation via CD4-Dependent Mechanisms

Products Related togp120,Nef,Vif Product# 2501Human Anti-gp120/160 HIV-1 pAb IgG Product# 1008 Recombinant HIV-1 nef (E.coli) Product# 1007 Recombinant HIV-1 vif (E.coli) INTRODUCTION HIV-1 infection is characterized by both chronic immune activation and severe CD4 T cell loss, eventually progressing to AIDS. After more than 30 years of research, it is still.

Posted on February 18, 2020

ImmunoDX

The V1V2 Region of HIV-1 gp120 Forms a Five-Stranded Beta Barrel

Products Related Product#1039 HIV-1 YU2 (M Tropic)Envelope Glycoprotein gp41 Product#101 gp120 Capture Elisa Kit Product# 1081 HIV-1 gp120 (ADA) Product# 1011 HIV-1 gp120 (subtype C) INTRODUCTION The HIV-1 envelope (Env) glycoprotein complex, consisting of glycoproteins gp120 and gp41, mediates the virus entry into the host cell. This heterotrimer is the major.

Posted on February 17, 2020

ImmunoDX

Antibody detection by agglutination–PCR (ADAP) enables early diagnosis of HIV infection by oral fluid analysis

Products Related top24,gp41,gp120,gp160 Product#1103 HIV-1 p24 Monoclonal Antibody Product#1091 Recombinant HIV-1 MN gp41 Envelope Protein (E.coli) Product#1001 Recombinant HIV-1 IIIB Envelope Glycoprotein gp120 (Baculovirus) Product#1024 Recombinant HIV-1 MN Envelope Glycoprotein gp160 (Baculovirus) Abstract Oral fluid (OF) is a highly effective substrate.

Posted on February 09, 2020

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