Blog (2)

An evolutionary role for HIV latency in enhancing viral transmission.

Products Related to Zika, WestNile, Dengue, Malaria, T.B, Chikungunya, HIV, SARS Product# 1039 HIV-1 YU2 (M Tropic)Envelope Glycoprotein gp41 Product# 1081 HIV-1 gp120 (ADA) Product# 1011 HIV-1 gp120 (subtype C) Product# 1031 HIV-1 gp120 (YU2) SUMMARY HIV latency is the chief obstacle to eradicating HIV but is widely believed to be an evolutionary accident providing no.

Posted on May 19, 2020

ImmunoDX

Bioinformatic analysis of neurotropic HIV envelope sequences identifies polymorphisms in the gp120 bridging sheet that increase macrophage-tropism through enhanced interactions with CCR5.

Products Related to Zika, WestNile, Dengue, Malaria, T.B, Chikungunya, HIV, SARS Product# 1039 HIV-1 YU2 (M Tropic)Envelope Glycoprotein gp41 Product# 1081 HIV-1 gp120 (ADA) Product# 1011 HIV-1 gp120 (subtype C) Product# 1031 HIV-1 gp120 (YU2) Abstract Macrophages express low levels of the CD4 receptor compared to T-cells. Macrophagetropic HIV strains replicating in.

Posted on May 18, 2020

ImmunoDX

Novel CD4-Based Bispecific Chimeric Antigen Receptor Designed for Enhanced Anti-HIV Potency and Absence of HIV Entry Receptor Activity.

Products Related to Zika, WestNile, Dengue, Malaria, T.B, Chikungunya, HIV, SARS Product# 1039 HIV-1 YU2 (M Tropic)Envelope Glycoprotein gp41 Product# 1081 HIV-1 gp120 (ADA) Product# 1011 HIV-1 gp120 (subtype C) Product# 1031 HIV-1 gp120 (YU2) ABSTRACT Adoptive transfer of CD8 T cells genetically engineered to express “chimeric antigen receptors” (CARs) represents a.

Posted on May 15, 2020

ImmunoDX

A tyrosine-based motif in the HIV-1 envelope glycoprotein tail mediates cell-type- and Rab11-FIP1C-dependent incorporation into virions.

Products Related to Zika, WestNile, Dengue, Malaria, T.B, Chikungunya, HIV, SARS Product# 1039 HIV-1 YU2 (M Tropic)Envelope Glycoprotein gp41 Product# 1081 HIV-1 gp120 (ADA) Product# 1011 HIV-1 gp120 (subtype C) Product# 1031 HIV-1 gp120 (YU2) SIGNIFICANCE The mechanism of incorporation of the HIV envelope glycoprotein (Env) into a developing particle is not well.

Posted on May 14, 2020

ImmunoDX

ERManI (Endoplasmic Reticulum Class I α-Mannosidase) Is Required for HIV-1 Envelope Glycoprotein Degradation via Endoplasmic Reticulum-associated Protein Degradation Pathway.

Products Related to Zika, WestNile, Dengue, Malaria, T.B, Chikungunya, HIV, SARS Product# 1039 HIV-1 YU2 (M Tropic)Envelope Glycoprotein gp41 Product# 1081 HIV-1 gp120 (ADA) Product# 1011 HIV-1 gp120 (subtype C) Product# 1031 HIV-1 gp120 (YU2) Abstract Previously, we reported that the mitochondrial translocator protein (TSPO) induces HIV-1 envelope (Env) degradation via.

Posted on May 13, 2020

ImmunoDX

Effect of cytokines on Siglec-1 and HIV-1 entry in monocyte-derived macrophages: the importance of HIV-1 envelope V1V2 region.

Products Related to Zika, WestNile, Dengue, Malaria, T.B, Chikungunya, HIV, SARS Product# 1039 HIV-1 YU2 (M Tropic)Envelope Glycoprotein gp41 Product# 1081 HIV-1 gp120 (ADA) Product# 1011 HIV-1 gp120 (subtype C) Product# 1031 HIV-1 gp120 (YU2) Abstract Monocytes and monocyte–derived macrophages express relatively low levels of CD4. Despite this, macrophages can be.

Posted on May 12, 2020

ImmunoDX

Annexin A2 antibodies but not inhibitors of the annexin A2 heterotetramer impair productive HIV-1 infection of macrophages in vitro.

Products Related to Zika, WestNile, Dengue, Malaria, T.B, Chikungunya, HIV, SARS Product# 1039 HIV-1 YU2 (M Tropic)Envelope Glycoprotein gp41 Product# 1081 HIV-1 gp120 (ADA) Product# 1011 HIV-1 gp120 (subtype C) Product# 1031 HIV-1 gp120 (YU2) Abstract During sexual transmission of human immunodeficiency virus (HIV), macrophages are initial targets for HIV infection..

Posted on May 11, 2020

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Structural insights into coronavirus entry.

Products Related to West Nile, Dengue, Malaria, T.B, Chikungunya, Sars, Zika Product# 17011 rSars Spike(S) Protein (EUK) Product# 63001 Recombinant West Nile Envelope E Protein (E.coli) Product# 17101 Murine Anti- SARS Monoclonal Antibody Abstract Coronaviruses (CoVs) have caused outbreaks of deadly pneumonia in humans since the beginning of the 21st century. The severe.

Posted on May 06, 2020

ImmunoDX

"Cytoplasmic domain effects on exposure of co-receptor-binding sites of HIV-1 Env".

Products Related to Zika, WestNile, Dengue, Malaria, T.B, Chikungunya, HIV, SARS Product# 1039 HIV-1 YU2 (M Tropic)Envelope Glycoprotein gp41 Product# 1081 HIV-1 gp120 (ADA) Product# 1011 HIV-1 gp120 (subtype C) Product# 1031 HIV-1 gp120 (YU2) Abstract We defined the effects of the cytoplasmic domain (CT) of the Env glycoprotein on co-receptor usage of HIV-1 by.

Posted on May 05, 2020

ImmunoDX

The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade.

Products Related to West Nile, Dengue, Malaria, T.B, Chikungunya, Sars, Zika Product# 17011 rSars Spike(S) Protein (EUK) Product# 63001 Recombinant West Nile Envelope E Protein (E.coli) Product# 17101 Murine Anti- SARS Monoclonal Antibody Abstract In 2019, a new coronavirus (2019-nCoV) infecting Humans has emerged in Wuhan, China. Its genome has been sequenced and the.

Posted on May 05, 2020

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